I've shot or been a part of shooting in excess of 100 animals with the 243 and 6mm Creedmoor. Half have been deer and antelope with the rest being coyotes, jack rabbits, prairie dogs, and other varmints. Most of these were taken with the plain jane Remington CoreLokt 100 grain 243 ammo with a half dozen deer and antelope taken with the 85 Sierra Game King BTHP in 243 and another half dozen with the 95 grain Barnes LRX in the 6CM.
6mm cartridges are generally a pleasure to shoot and easy to carry as they don't require a long heavy barrel to shoot well.
Attached is my first big game animal taken with a 243 Winchester M70 and the 100 gr CoreLokt. This antelope was taken in 1988 at around 300 yards based on where my dad told me to aim and where the bullet hit using my drop chart since there were no range finders back then.
Also attached is my daughter's first antelope taken at 185 yards with the 6CM and the 95 grain LRX.
6mm cartridges are fun!
Jay