Lead ingestion health risks

[Article 4]

I’m sure I will get flamed, but the current consensus at an academic level is that existing guidelines are overly generous, especially in children. The basic gist is that any blood lead level is harmful (but as I’ve said, we all die of something).

I would say that if you were trying to study the effects of ingesting game on BLLs, you would try to look for statistically significant increases in a population, not just whether those who consume game had levels requiring intervention.

no flaming. Just a good discussion as it sounds like you are familiar with how it work

So statistical significance is important, and measure P Value (maybe some folks read this and aren't familiar) is how we gauge it.

P value is generally not considered part of a small sample set study - which these are. P values of 0.05 would be min to achieve significance. A P value of .0005 would be very significant. The lower the number, the less variance in the data and more reliable it is

To achieve that kind of data, we need a control group, and randomization, and blinding of the data with at at least 60 people and more likely something around 200-300 to show any hope of a really good of P Value.

These studies weren’t powered to look at statistical significance, they merely looked at trackable levels. I included them only to answer the OP question of does it transmit and is it possible.

 

[Article 4]

I’m sure I will get flamed, but the current consensus at an academic level is that existing guidelines are overly generous, especially in children. The basic gist is that any blood lead level is harmful (but as I’ve said, we all die of something).

I would say that if you were trying to study the effects of ingesting game on BLLs, you would try to look for statistically significant increases in a population, not just whether those who consume game had levels requiring intervention.

A side thought
I doubt I will die from lead poisoning lol - nor will many of us. I have learned a lot from this research and to me, the most urgent need around this is potentially children or fetus...adults maybe not so much unless you live someplace like Greenland or Norway or are packing in 100 ducks a year without being diligent about your butchering.

As far as statistical significance, I found this NEJM study talking about toxic levels in kids. If anyone wants to refute the NEJM then wow...there is nothing that will please them

Well designed, good P Values etc...not directly answering the OP question but maybe shedding a bit of light on the "what is truly toxic part)

https://www.nejm.org/doi/full/10.1056/NEJMoa022848

 

[Hoopleheader]

no flaming. Just a good discussion as it sounds like you are familiar with how it work

So statistical significance is important, and measure P Value (maybe some folks read this and aren't familiar) is how we gauge it.

P value is generally not considered part of a small sample set study - which these are. P values of 0.05 would be min to achieve significance. A P value of .0005 would be very significant. The lower the number, the less variance in the data and more reliable it is

To achieve that kind of data, we need a control group, and randomization, and blinding of the data with at at least 60 people and more likely something around 200-300 to show any hope of a really good of P Value.

These studies weren’t powered to look at statistical significance, they merely looked at trackable levels. I included them only to answer the OP question of does it transmit and is it possible.

I’m sure I agree with you, but three beers in you can probably pull a fast one on me

 

[Article 4]

I’m sure I agree with you, but three beers in you can probably pull a fast one on me

Hell i might have quoted Shakespeare.
Who says i don’t have a double bookers bourbon going?

 

[Hoopleheader]

A lot of these threads would only be 2 posts if Form jumped on as soon as they appear, pontificates some kind of a 2 or 3 sentence discourse, and then shut the thread down...

When are we going to get a “praised be” reaction emoji for such instances