It makes an utter mess of the hind quarters, the femurs and hip are usually in dozens of pieces.
People that think deep penetrating, hard bullets are the way for shooting animals heading straight away from them- haven’t tried it very much. The general response from the animal to sprint away. Lots of times the bullet gets stuck in the stomach when full of grass- even large 338’s.
Conversely, if you’ve done it much, you understand that bullets that penetrate 12’ish inches and create very wide wounds are much more effective. Put an 130gr TMK into the rear end it basically any animal and it’s utterly destroys the use of their back legs. Animals drop immediately and tend to turn sideways allowing an immediate follow up chest shot.