I'll put in another vote for any of the three. I would add that more important than the cartridge is being prepared for a follow up shot if needed. I've seen a few elk lay there without moving for 10 to 15 minutes, only to either jump up and run or try go get up when the hunter approached. My last bull was still alive 20 minutes after the shot when I finally made my way over to him and he required a second shot to kill him. The first hit was double lung with a 200 grain Partition. My bull before that took a 225 grain Accubond slightly quartering to that shattered the on side shoulder and wrecked the lungs. His front legs collapsed at the shot, then he just stood back up and slowly started walking. A second round finished the job. I've killed a lot of deer, and rarely seen one take that kind of punishment. Elk aren't bullet proof, but sometimes they don't know that they are dead right away.