Here is my experience, for reference I am small- (5’7/ 150lbs)... I have mostly carried a G19 with RMR in the woods in NH. My favorite carry is a Gunfighters Inc. Kenai Chest holster but I don’t like wearing it under my AGC bino harness. For me the bulk is uncomfortable, especially in late season with bulky layers. I tried the AGC holster but the RMR interferes and I can’t fully holster the pistol. I could lose the RMR to make it work, but at this point I do shoot better with it so I’m not ready to do that. Also for anyone considering an RDS, remember to consider glass fogging which will happen transitioning from truck to cold. I initially thought this was a dealbreaker, but I’ve adapted.
A lot of the time I am wearing my hunting saddle into the woods and I don’t like mounting a pistol onto my saddle belt, nor elsewhere on my waist when climbing with a saddle. When I wear a framed pack I use a OWB holster with a QLS mount, or use the Kenai with the pack, no issues there.
In part to lighten and slim down my backup carry, I recently purchased a 43x MOS, CHPWS plate, and Holosun 507k. Still find issue with the RDS fitting with an AGC holster (AGS doesn’t claim it will work) but I think a 43x Kenai under the bino harness will be a better fit for me than that the 19. If I were a bigger person I imagine I would have no issues carrying the 19 like this.