I was making a bad joke sorry.I feel the same way. Have a neck injury so avoid at all costs. Guide "required" a 300 as minimum. But after I saw the damn thing it kind of felt T-Rex like. My 300 with a 180 TTSX went the entire length of the animal front to back and lodged just at the ass. It still ran and I put a shot in the neck in the brush. Shot the rest of the ranch up with a 7 Saum and Berger bullets.
If any "guide" has a "caliber" restriction I'd stay far away from them personally.
Animals sometimes run after being hit, man. From coyotes to buffalo and 22 LR to 404 Jeffery I've seen them all both die right there and run miles.
One thing that's consistent in high enough volume and with any bullet diameter in that I've seen, is that heavy for caliber tipped style bullets of good design and construction lead to the quickest kills.