I hunt in literal forests of jumping cactus every year, the big mulie bucks live/hide in there.I added an insole cut from oak tanned saddle leather to mine to try to keep the mesquite and cactus out. So far so good, but quail season in November will really tell the tail. One thing about that insole is that it’s slick and your toes hit the end of the boot on steep downhills. I am considering cutting a new set of insoles and putting them in flesh side up to reduce that.
My guess is that you might be safe with jumping/teddy bear cholla on the soles, but I could see it getting through the toes and the top of the foot. Glad I don’t have that stuff over here. It’s awful stuff.