I appreciate the input from everyone. I’m not concerned about transmission from handling the head or processing the meat, more so the ingestion of the meat given the proximity to a confirmed CWD case. Guess I’m just worrying myself with this hypothetical that my deer could be positive as well. I guess the area we were hunting in hadn’t had any confirmed cases till this year which I didn’t know about till after my buddy got his tested, so really wasn’t a “need” to be concerned. Will definitely be more cautious next year hunting in that area.
Lots of interesting tangents that came up and through I’d chip in my understanding of CWD and prions:
Prions aren’t alive like bacteria or viruses. They’re misfolded proteins, and they can stick to metal, plastic, soil and so on, which is why labs use strong bleach or NaOH when they are cleaning equipment that touched brain or spinal tissue from an infected animal. That part is true.
What they do not do is grow or multiply on tools or carcasses. If you cut through the brain or spine of a CWD-positive deer and then use the same knife on another one, you can physically move some prion material around, but it does not “infect” the second carcass because it is already dead. It is just trace contamination, not an actual transmission pathway like you see in live deer. Nothing happens to that second carcass because it is already dead and prions cannot infect, amplify, or replicate in dead tissue. It is just physical transfer, not biological infection. Think about prions like glitter. You cut through a bag of glitter, you get glitter on your knife and can move that glitter around between surfaces, but it doesn’t replicate. And still, you’d have to be actively cutting through spinal/brain tissue to actually pick up a significant load of prions. Whereas cutting through meat doesn’t always necessarily mean you’ll pick up any prions, and if you do, it would be a very very minimal load.
For humans, there are still no confirmed CWD cases despite a lot of hunters eating deer from CWD areas over the years. Lab work suggests humans have a strong species barrier, but agencies still recommend not eating meat from a known CWD-positive animal as a precaution.
So, prions are hard to destroy and can stick to surfaces, but they do not behave like bacteria, they do not spread in dead tissue, and the real issue is deer-to-deer or environmental transmission. The human risk picture has not shown any real-world infections even with long-term exposure. I get the risk of human transmission is apparently nearly impossible, but I would still be concerned about eating a confirmed positive CWD infected deer, but cross-contamination between surfaces isn’t something to be too concerned about.