Will you be happier overall, while remaining financially capable of doing all the things you & your family REALLY want to do? I took an almost 40% cut to be an hour closer to home, get most of the summer off, spend my time at work doing the things I really love to do, and get out of the political bs & neverending paperwork that come with a tenure track faculty position in the sciences. I had spent 25+ years climbing the ladder & advancing my career while working with the best scientists in their field...and I decided I didn't want what they had if it meant sacrificing more time with my family.
It was the best move I ever made. I had my first summer off last year in 28 years, and it was more than worth the pay cut. A garden, camping, hiking, fishing, scouting, making memories with my family...absolutely worth it.