Thanks. If these were really so great, as claimed, then I would think that the industry (or at least some of the more reputable makers) would make it easy to find the data to back it up. Note - I am not just throwing stones at the supplement/vitamin industry. Same goes for pharma IMHO - as I yesterday was looking for a mortality table from the Supplementary Appendix of the EUA study for the Moderna vaccine (out of curiosity). It's not easy to find
Sort of. There are many very good medications that most people would have trouble finding or understanding the evidence that shows they are good. There are many commonly accepted truths (to include in medicine) that have nothing but a hypothesis to support them.
I try to stay with the evidence, but sometimes there is not good evidence and a hypothesis is the best one has. As long as you know the weakness of that, it is fine to run with it untill better data is available.
There may be supplements worth pursuing, but having failed to find one I have stopped looking as it is a low yield area. Example, supper beats clearly low BP, however not everything that lowers BP improves long term outcomes. Most likely it is the nitrates in the beats, nitrates (without a specific reason to use them such as angina) are not associated with improved outcomes. So, if I'm going to need BP meds I would personally opt for the cheaper ARB (such as losartan) than the more expensive and unproven supper beats. In the end, I really care only about the improved long term outcomes, not a number (other than to the extent the number helps me get to the outcome).
I spend a lot of time taking people off beta-blockers (BB) if the BB is only for blood pressure. While BBs get the number down, if there is not another reason for BBs, they don't improve outcomes. So, they treat the number, not the patient in the case of blood pressure.
Because BBs do a good job treating the number they once were first line therapy for BP control and are still prescribed for it commonly. The hypothesis was legitimate, but did not stand up to investigation.
There are very good reasons to use BBs though, and suddenly stopping can be dangerous, so no on should stop them without involving a healthcare provider.