BPC 157 Peptide: Injury Update

Poser

WKR
Joined
Dec 27, 2013
Messages
6,316
Location
Durango CO
I posted in another BPC 157 thread that I was doing a cycle of this peptide and would report back. I have 3 unrelated injuries that compounded on me.

On April 19th, we had a 5 inch powder day at the local ski area. For whatever reason, ski patrol had not marked any spring obstacles, of which there were a lot, that morning before opening the lifts. They started marking them after opening. I was first chair and shredding fresh powder at 40+ MPH when I hit a ~2 foot deep hole (lt was like there was a 5 gallon bucket under a thin layer of snow) that was covered with fresh snow and took a pretty good shot resulting in a slightly torn rotator cuff. That healed enough inside of 10 days that it did not impede my day to day life: I could comfortably get a hoody (couldn't put one on or take one off initially) on and off, for example, but super limited in the gym as any weighted shoulder stress hurts and aggravates the shoulder.

About a week later, I was carving through my neighborhood on my longboard, maybe 15 mph, when a car abruptly pulled out of a driveway in front of me. I went down on the pavement pretty hard. I was wearing a helmet, which was good because I smacked the shit out of my head. Lost some skin on an elbow, but jammed the absolute shit out of my right thumb. I thought it was broken for sure, but turns out it wasn't after getting Xrays. Anything that required thumb pressure like opening a screen door was a no-go. I had to turn my key ignition using my fingers.

My left meniscuses fell apart about a year and half a go. There was no trauma. Just went mule deer hunting one weekend and later that week, it crumbled. Recovery was 3-4 months. I think I started putting stress on my knee again (squatting, deadlifting, hiking) after 3 months, but it was super tentative for another month and then eventually stabilized with scar tissue and possibly hardening up enough that its non issue for my lifestyle: strength, training, snowboarding, hiking, backpacking, hunting, peak bagging. I'd be super hesitant to play a pickup game of flag football or a basketball game that is anything more than casual, but I don't play any team sports anyway. During that injury, I went through the whole medical pipeline: MRI, 3 rounds of X rays (one for my GP, another for the orhtos PA and another still for the Orthro who wanted to see the meniscus load bearing) referral to a orthopedic surgeon which required a visit to a GP, an appointment with a Ortho PA (all of this took ~6 weeks) to finally get a ~10 minute appointment with a surgeon who told me to make some lifestyle adjustments come back when I need a knee replacement.

During this recovery timeline, I started taking Boswellia Serrata, Turmeric/Curcumin, Glucosamine, Magnesium Glycinate specially to address the injury. There's at least some data to suggests these may be directly beneficial, but opinions vary. I've stayed on those supplements since then. I'll also note this is addition to taking daily vitamin D, zinc, fish oil and boron, which may or may not have peripheral benefits, depending on who you talk to. These may or may not play a factor in recovery from the next injury.

Early May, I perceived some slight knee discomfort on my right (opposite) knee. I backed off a bit for a week, and it seemed to immediately dissipate. On May 9th, I did my usual spring/summer training hike (1000 feet in .8 miles). On May 10th, I did a big, epic backcountry/ski mountaineering day. Felt great, had a fantastic day: skinned, boot packed, use crampons and rode a fantastic 2700 foot descent. It may have been the best I've ever felt moving in the mountains, just an unbelievable day out:


3107090175872074718.jpg
On May 11th, I again did my training hike. On May 12th, a rest day, I went to work, did my normal 40 minute casual walk after lunch, felt fine. Went home, sat in a chair working for another 2 hours. Stood up and my meniscus fell apart.

I started taking BPC 157 on May 14th. I used this oral capsule: https://infiniwell.com/products/bpc-157-rapid-pro
This was at the informal suggestion of a surgeon who goes to my gym who I have casual conversations with. He wasn't giving medical advice, just mentioned that he's a fan of peptides and that the data he had seen on this oral version looked promising. I thought I would try this first vs DIY injections.

Starting May 16th, I spent an excruciating 8 days completely laid up. Zero range of motion in my right knee. I had to use a walking cane to get out of bed and out of the recliner -could put 0 weight on my right leg. I could not bend my knee enough to get in my truck (not sure I could have even pressured the brake pedal anyway). I couldn't figure out a way to step over the tub into the shower. I sweated all night, I would get freezing cold in the morning to the point that I was under 3 blankets and my teeth were chattering. I iced my knee through the day, kept it elevated, rode out the pain. I finally broke down and took some leftover painkillers my GF had from ACL surgery so I could get some sleep. That was maybe 3 nights. That was 8 days long and it pretty intense all the way around: totally laid up, totally in pain and fairly helpless. I lost 10 pounds with little appetite. I didn't seek any medical treatment as the setup and immediate symptoms were exactly the same as last time. What was different was my body's reaction : it was super intense and very much an overreaction to the injury, but I seemed to run the recovery cycle in a very expedited manner. By day 9, I started getting around better and could get in the shower. By day 10, I put the walking cane up and was able to get in my truck. From there, every single morning was dramatic improvement over the previous one. I started taking 3 slow ~30 walks a day around the neighborhood. Almost 3 weeks after the injury, I went on my first hike, have only the slightest limp and, based on experience from last time, the knee is ready for some stress. I'm going to start doing some box squats and regular conditioning this week and see how it responds, but last time I hit a tipping point where the more I moved and stressed it, the better my knee responded and my intuition says I am there. Good thing because I had some pretty serious atrophy happen during those 3 weeks.

It seems to be the case, from my prior experience with this injury, that I experienced a 3 month recovery in 3 weeks. My thumb has healed up pretty well. Its still a little tight when I fully flex it, but it doesn't' hurt. My rotator cuff, however, is only moderately better, definitely not fully healed after 6 weeks. You can definitely make the case that some experience with the same injury was a factor in an expedited timeline. There is also the factor of the aforementioned supplements potentially helping with inflammation and possibly resulting in some higher quality synovial fluid. I'm not discounting either of those, but based on last time, this was a pretty remarkably expedited timeline of recovery. I'm going to lay off the BPC 157 Peptide for a month and do another cycle in July.

I'm hesitant to make any strong claims here and my GP is going to not be happy once I fill him in on my self experimentation, but that was my initial experience with BPC 157.
 
Great write up, thanks for sharing. Valuable info and datapoint for others to reference. On the Key Disruptive/Phantom setup for your split 👌🏼
 
Hate to hear about all the injuries you've been dealing with lately, but glad to hear healing has been expedited to some degree.

I was in Steamboat Springs with my family, snowboarding first chair the morning of April 10th when I hit an icy patch and lost control, resulting in a fall and hyper extension of my left elbow. Tore my left distal biceps tendon and strained basically everything in that elbow region. Had MRI to confirm on April 14th and then had surgery the following Monday April 21st. I asked the surgeon and a PT about BPC-157 and they both simply said the research seems to support that it might help. Surgeon wanted me to wait two weeks post op to start, but that's the earliest I could begin injections because I was in a full splint for two weeks anyway.

I started injecting BPC-157 into the site of the reattachment on my forearm on May 8th, two injections a day of 250mcg for two weeks, and then after two weeks, switched to one injection a day of 500 mcg. In total, I'll end up injecting 20 mg's of the peptide into the injury site, once I'm done with this second vile. Surgeon won't let me start PT until 8 weeks post op. I've been in an ACL type brace which limits extension (increasing from 40-0 by 10 degrees each week) since May 6th and I'm more or less able to fully extend my left arm again as of this morning. Pronation and supination are somewhat limited, but overall, I think the BPC-157 has helped speed up my recovery.

Once I start PT for the elbow, I plan to start a round of injections for my left Achilles which has been an on/off issue for 10 years now. I'm hopeful it'll help, but skeptical anything can if I'm being honest.
 
On the Key Disruptive/Phantom setup for your split 👌🏼

Good eye for detail. That was a tough pill to swallow financially, but that's a great setup. I don't miss soft boots one bit on the downhill. The only downside I've found is getting locked into the bindings while on dicey changeover terrain.
 
Hate to hear about all the injuries you've been dealing with lately, but glad to hear healing has been expedited to some degree.

I was in Steamboat Springs with my family, snowboarding first chair the morning of April 10th when I hit an icy patch and lost control, resulting in a fall and hyper extension of my left elbow. Tore my left distal biceps tendon and strained basically everything in that elbow region. Had MRI to confirm on April 14th and then had surgery the following Monday April 21st. I asked the surgeon and a PT about BPC-157 and they both simply said the research seems to support that it might help. Surgeon wanted me to wait two weeks post op to start, but that's the earliest I could begin injections because I was in a full splint for two weeks anyway.

I started injecting BPC-157 into the site of the reattachment on my forearm on May 8th, two injections a day of 250mcg for two weeks, and then after two weeks, switched to one injection a day of 500 mcg. In total, I'll end up injecting 20 mg's of the peptide into the injury site, once I'm done with this second vile. Surgeon won't let me start PT until 8 weeks post op. I've been in an ACL type brace which limits extension (increasing from 40-0 by 10 degrees each week) since May 6th and I'm more or less able to fully extend my left arm again as of this morning. Pronation and supination are somewhat limited, but overall, I think the BPC-157 has helped speed up my recovery.

Once I start PT for the elbow, I plan to start a round of injections for my left Achilles which has been an on/off issue for 10 years now. I'm hopeful it'll help, but skeptical anything can if I'm being honest.

The surgeon I informally spoke with didn't seem to think that localized injections make any difference. If the compound is in your bloodstream, its in your blood stream. He said that he injects them in the belly for all injuries. Doesn't seem that it would have any negative impact, but, based on that, it would seem that your achilles would have healed, at least somewhat, along with the elbow.

Could be that the body has a way of prioritizing injuries? I suppose that's my hesitation with drawing conclusions: a more severe injury in a far less vascular part of the body healed much faster than a more minor injury in a more vascular area of the body for me. I'm not sure what to think about that.
 
Good eye for detail. That was a tough pill to swallow financially, but that's a great setup. I don't miss soft boots one bit on the downhill. The only downside I've found is getting locked into the bindings while on dicey changeover terrain.
Definitely are a game changer. I personally prefer the Phantom Slipper boots. Sold my Disruptives earlier this season. Slippers have much more articulation and a lot lighter. They still ride really well. I’ve popped out of my bindings a couple times while on pretty serious terrain in Valdez from not having the bails as absolutely as tight as they’ll adjust to, as well as having ice buildup on the welts of the boots. As long as you are diligent, the system as a whole is fantastic.
 
Definitely are a game changer. I personally prefer the Phantom Slipper boots. Sold my Disruptives earlier this season. Slippers have much more articulation and a lot lighter. They still ride really well. I’ve popped out of my bindings a couple times while on pretty serious terrain in Valdez from not having the bails as absolutely as tight as they’ll adjust to, as well as having ice buildup on the welts of the boots. As long as you are diligent, the system as a whole is fantastic.

For me, the Disruptives were more of a fit choice. I have a narrow foot with oversized toes and the Disruptives have a rather generous foot box. I was able to order them through a local store which I could return them through if they didn't fit well and also came with bootfitting. After trying them on with some a few different insoles and standing around the store for 45 minutes, I decided to leave them stock and could come back with any customizations, but I didn't need any -they fit me pretty much perfectly out of the box.

The Phantoms had already been discontinued and were no longer available in my size, though, several of my partners use them. I probably would have gone with them had they not been discontinued, but I am a little skeptical on BOA dials in the backcountry. I didn't really want to mess with customizing a ski boot when the Disruptives seemed to already have the flex I was looking for.
 
The surgeon I informally spoke with didn't seem to think that localized injections make any difference. If the compound is in your bloodstream, its in your blood stream. He said that he injects them in the belly for all injuries. Doesn't seem that it would have any negative impact, but, based on that, it would seem that your achilles would have healed, at least somewhat, along with the elbow.

Could be that the body has a way of prioritizing injuries? I suppose that's my hesitation with drawing conclusions: a more severe injury in a far less vascular part of the body healed much faster than a more minor injury in a more vascular area of the body for me. I'm not sure what to think about that.
Interesting, as my surgeon and PT both favored site injections over oral. Literature out there can support both depending on where you look. I may go with both BPC157 and TB500 combo for the achilles, will report back after I complete that cycle, probably be around mid August.

Biggest issue is I'm actively training for another ultra that takes place end of August, so I'll be trying to heal while continually stressing the tendon. After my elk hunt this September, if the initial protocol helps at all, I'll take October off from running and see if another round with active rest (no running but rowing or bike for cardio) can allow for advanced healing.
 
I have had good results also using a nasal spray application of BP157. I messed up my shoulder and didn’t want to do surgery so I went the slow route of PT to get it back to being usable and while its not 100% it’s good enough and that’s when I tried 157 and was impressed with the results. I then had to have two surgeries a week apart to deal with a tumor and I used 157 again to help speed recovery. I tell anyone I meet who mentions an injury to check into it.
 
Interesting, as my surgeon and PT both favored site injections over oral. Literature out there can support both depending on where you look. I may go with both BPC157 and TB500 combo for the achilles, will report back after I complete that cycle, probably be around mid August.

Biggest issue is I'm actively training for another ultra that takes place end of August, so I'll be trying to heal while continually stressing the tendon. After my elk hunt this September, if the initial protocol helps at all, I'll take October off from running and see if another round with active rest (no running but rowing or bike for cardio) can allow for advanced healing.

Could you PM me where you're sourcing your injectable BPC157? I've been debating trying it for years for elbow tendonosis that flairs up pretty regularly and predictably, but think I'm finally ready to give it a try...
 
I've tried injectable BPC-157 from Core Peptides and two other companies I forget the names of. I didn't notice any difference in healing or recovery. I have no way of knowing if these sources are legitimate. I never tried the oral version.
 
Back
Top