You would have to follow them more than a year to make the conclusions you are making.
What conclusions do you think I'm making?
I'm not concluding that the LMHR phenotype is the ideal mode of being, or necessarily that it's even safe. I don't know. We're in totally uncharted territory, way beyond the borders of our knowledge or common modern experience. Yes, some large populations have basically eaten this way since forever (particularly in places like my home Alaska), and probably were LMHR, but there's virtually no data in modern people to examine.
However, a common man can observe that, by all accounts, the LMHR types appear to be thriving, despite LDL levels vastly beyond what conventional medicine considers dangerous. This is largely in middle aged people, who by virtue of age alone should be showing significant heart disease. Just to be considered for the LMHR study, participants have to have been on low carb/ketogenic diets with elevated LDL for years.....at a minimum this is all a serious challenge to the conventional wisdom of the diet heart hypothesis that we've all been stuck living under for most of our lives.
Modern medicine has made an incredibly bold claim and stuck with it for decades. It's become dogma, and has radically affected what we eat. The diet heart hypothesis entails a belief that ancient foods, the foods that constituted the vast bulk of the available calories in many areas of the non-agricultural world for most of human history....somehow those foods are the major cause of heart disease.
Huh. Well, maybe. That is a bold claim. What evidence is there for that? There ought to be some tests about that. I'm no longer willing to just default accept whatever "The Science Tm" says, especially when it goes so heavily against plain common sense and observations in my daily life. Nor the historical and anthropological evidence of Alaskans (or Sami, or plains Indians, or Massai, etc) or early explorers. The burden of proof for such a claim lies on YOU modern medicine.
In short, it's not easy to declare what is true and complete and ideal in a complex system like the human body...but it's not all that hard to poke holes. It's doesn't take much to demonstrate that what we think we know is insufficient and probably isn't true. My frustration is that most of our medical system seems uninterested or incapable of considering contrary evidence. It is unfortunately quite possible to have better health outcomes by letting common sense and common observation be your guide, rather than to do submit to whatever your doctor tells you if he just relies on the AMA, AHA, ADA, USDA, FDA, etc. to do his thinking for him.
I'm not claiming that we should all have LDLs of 300-700. I don't know what the ramifications of that is. I suspect there's probably downsides that I don't know of. But I do know that there are more and more people like me that, rather inconveniently, and totally contrary to the predictions of "Modern Medicine Tm", keep on not dying of heart disease. Shocker.
My conclusion in all this? Something is wrong about this story we've told for 60 years. Also, our medical institutions are still made up of people, and are just as likely to engage in dogmatic, delusional group think as the rest of us mortals.
Heart disease is a /long-term disease.
Fine and yes, heart disease is a long term disease, and this study only lasted one year. But of note, the average age was 55, and average length of time on an ketogenic diet with high LDL cholesterol was 5 years. And of the 100 participants....zero would be considered high risk from their baseline plaque or plaque progression. To be considered for the study you already had to have been on it for 2 years minimum (maybe 3? can't remember) before the study began. If the diet heart hypothesis was true, shouldn't there be something like a dose dependent response to spectacularly high cholesterol? We're not talking about people with just elevated levels of LDL, these people are several standard deviations away from what's been considered dangerous.
Where is the signal?
I would also mention that you can have high HDL and low Triglycerides eating a shit pile of carbohydrates, they are not mutually exclusive. Those 2 factors are more indicative of exercise and metabolic condition than anything. For example, my HDL is 80+, Triglycerides sub 50 and I eat 300-400 carbs a day.
True and I don't dispute that. For me, what carbohydrates I eat seem to matter. Also for me and many others, it's much easier to eat carbohydrates to excess and go on a blood sugar roller coaster. But that's not everybody, and that's fine.
Side note, it was interesting to me that in my quest to pass a test crash my LDL numbers in the Army, by nearly completely switching from a fat based metabolism to carbohydrate based, I only gained like 12-15lbs of fat in 5 weeks. I ate carbohydrates excessively, but very low fat. Yes I got fat, lost muscle, got sick all the time, skin problems, multiple rolling cold sores outbreaks, massive blood sugar and energy level/mood problems. But I didn't really get all that fat. I highly suspect that had I added more fat with the carbohydrates I would have gotten fatter more quickly. Interesting.
All this to say, I think many diets can work. IMO, being a reasonable bodyweight, lean, muscular and exercising hard are the most important, really terrible genetics withstanding, for long term health.
Concur. I forget the tribe, but there was a tropical indigenous people I read of that consumed something like 85% or more carbohydrates, with no imported food. Like several indigenous populations uncorrupted by modern food-like substances, they seemed to live long healthy lives absent modern chronic diseases. Likewise there have been several extremely low carb populations that seemed to do equally well. Usually more muscular however. Anyway, there's more than one way to live well.