Texas' efforts at closing the border is driving that traffic westward, so you may see more activity this year than prior years. Depending on the corridor, some of those places will have cartel members in LP/OPs on our side of the border, glassing and directing mule traffic. They genuinely desire to avoid contact with anyone, but they are armed - it would be a very good idea for you to also have something on you that clearly identifies you on-sight at a distance as a gringo deer hunter, and not la migra or any other law enforcement. That said, if you're good at your own mule deer glassing game, you'd have a good chance of seeing them before they see you. Then, just avoid them.
Another item to consider would be contacting a game warden in the region, and/or one of their wildlife biologists, and directly ask them if there are certain places they would recommend you not go, to avoid any of that cross-border traffic. If you've studied your maps/OnX in advance, it would also be a good opportunity to segue into discussing places you're considering hunting. Don't directly ask for good spots, but demonstrate you've studied the heck out of the area, and get their hot/cold thoughts on specific mountains, areas, etc. As long as it looks like you've done a lot of homework and aren't just asking where the big bucks are, they're generally helpful. But that discussion about cartel hot spots would probably make a great opener.