No I have not hunted moose, other than once with my dad when he drew a moose permit, but that doesn't mean I don't know how bullets work. I like bullets that stay together and go all the way through an animal. ELD-X bullets aren't going to go all the way through a moose. I also wouldn't have confidence that they could even make it through the shoulder of a moose into the lungs. I have no doubt they could kill a moose with perfect shot placement. But there are many other bullets I'd use over the ELD-X. I only used them for deer because they're extremely accurate, and I knew they'd be good enough for a couple of small doe mule deer. I hunt elk every year and I certainly have never used that bullet.