My 19x is usually my go to with the 17 round mag in the gun during summer months and the 19 round mag during colder months. Switched the barrel out for Griffin ATM with micro comp and put a TLR 7-A on it. It has Trijicon suppressor sights on it for shooting suppressed at the range. I'm pretty happy with the setup, just think I want to have the slide milled for an RMR now.
Sometimes during the winter I just carry my FNX 45 tactical that's converted to 460 Rowland pushing 230gr Gold Dots at 1,200fps. Kind of an equal opportunity of running into a two legged turd or a pissed off moose.