FYI - I had the same issue with my VX5 after I received the CDS. I re-installed the factory turret and re-zeroed the rifle. I then reinstalled the CDS and it fixed the problem. You can can also reach out to Leupold cs for trouble shooting.
I have noticed my groups change depending on what kind of target im shooting at. My eyes, brain etc just focus and hold better with certain target shapes/sizes better. Circles are the worst for me. It gives me anxiety or something trying to hold in a circle. Grid targets with hrs angles to line up play better with me. Color can affect it too. Maybe try using the same target style you got good groups on at 100 (that target you have pictures is my favorite zeroing target).