Loper, you’re getting loads if options but don’t start overthinking it. One of my buddies has used a 6.5 Arisaka that is sporterized for 60yrs and has killed numerous elk with it, most were bang-flop. As for a muzzle brake, I’ll pass myself. My archery partner has one on his rifle, went with him once, no more, too freaking loud for me. I guarantee if you put it in the boiler with the 6.5 the critter will go down in the ranges you’re talking about. Conversely a borderline hit with the 06 could result in along chase or lost animal.