InReach is nice, depending on weather and location, at least in Alaska, you still might be on your own for several days.
Leaving some depends, some times it is the best option. I have told a friend to go get help when I hurt my ankle and couldn't walk. This was as a kid, I crawled a quarter mile or so before family showed up with a 4x4.
One person dying is bad, but two dying is worse. Each situation is different. The more one understands the risks from both a medical and a technical skills side of things, the better equipped they will be to make a call.
Personally, I would send a buddy to try and find help before I lite off an SOS for a hurt foot in many situations. But even this depends on weather and expected conditions. The safety of whoever comes to help is as much my concern as my own and my buddies safety.
The counter point, is waiting too long can endanger everyone involved. Say a broken rib from a fall with a stable patient. You try to walk out, but as night closes in it because clear a tension pneumothorax is forming, now rather than in daylight with little stress, you are asking for a helicopter to extract some who is crashing at night.
As with everything, you have to make your best judgement call using the information and knowledge you have.