I'm starting to think I should as well.
I know folks here locally that kill elk with 243 Winchester's and 6 Creed's.
They pass on difficult shot opportunities, and wait for the broadside or a head shot.
I use the 110 Accubond in my 25 Creed Pachmayr Dominator (14" barrel).
Even with a 14" barrel (Krieger) my muzzle velocity is 2726 fps, which gives me just over 1850 fps at 500 yards. You can see I have the accuracy at 500 yards for hunting, even in windy conditions.
1800 fps is the minimum impact velocity for the AB to work right.
I don't plan on shooting that far with the Dominator.
I do plan to use it for a cow elk in the future though.
The 1911 frame makes it more difficult to be accurate with infield positions than my XP-100's
25 Creed, 25 Sooper (25-308 Winchester), 25 SAUM, 25 PRC are all options for a short action set-up. I have a 25-284, but it is on a single-shot action. With a magazine, you would need to go to a long action, or use a single-shot action.
My 25 PRC
Some initial load development at 100 yards, shooting prone.