I tapped a moose with a 150 Accubond at lowish velocity once (2700-something FPS MV, about 120 yards, maybe 2500 ish impact?). Went clean through him on the diagonal like a hot knife through butter (2.5 to 3 ft of moose I estimate). On another occasion, I shot a bull elk with a 140 grain 7mm (2200 FPS impact velocity), likewise on the diagonal (about 2 ft of elk), and it likewise went clean through. Destroyed the vitals in both cases, and provided great eating for me and mine for several years.
I would therefore be 100% gobstruck if a 140 grain bullet with better sectional density than either of those didn't do the exact same thing.