SilencerCo Hybrid for the centerfires. It's bored out to .46 and build to use up 5o and including .338 Lapua (22" barrel minimum iirc) and .45-70 (18" barrel, not limited to trapdoor loads either). You can swap frontcaps if you want, using a smaller bored frontcap will quiet down the .223 a but more but don't accidentally leave it on there when you shoot .450 through it. The other end is standard "Bravo" pattern, so you can go direct thread or spend way too much money on mounts, unfortunately for .450 I think you're still limited to ASR, Area 419/Hellfire, and KeyMo (using JMac Customs brakes) unless Griffin got their mounts off the ground. since your .223 and .450 are almost certainly going to use different threads (1/2"x28TPI and 5/8"x24TPI respectively, or perhaps the 3/4"x24TPI for the big bore) you'll be looking at either a mount system or two endcaps. The good news if you can also shave a few ounces by going to Ti front and endcaps if you want to spend way too much money on it.
Quick aside on mount systems: I appreciate systems that minimize the risk of cross-theading and reduce the amount of twisting, so KeyMo is very much on my radar right now. ASR has a reputation for being less foolproof, although perhaps I'm a fool! But threads+ratchet seems less suited to on/off cycles than taper+threads or taper+retainer. Direct thread is the lightest and adds the least Length, often you'll find you're adding 4-5oz and an inch to the end of your rifle to use a mounting system.
For rimfires, tough to go wrong. I have two, a Spectre II and a Sign SRD22, my friends have the Sparrow (replaced the Spectre). Most rimfire cans come in two versions, either a tube with baffles that index off each other or the Oculus/Erector pattern of baffles that attach together to form the body without a outer tube. I personally don't see a reason for the tubeless designs other than looking cool, I haven't seen good evidence that they're quieter or cleaner and my suspicion that most people either run 3 baffles or all the baffles is so far pretty well borne out. SilencerCo's Switchback and the Energetic Nyx straddle this line as a modular can that has two sections of baffles so you can run it short or long, trading suppression for size. If I were buying today I'd get the Nyx. There are also microcans (Bowers Bitty, TacSol has one, etc) but on a pistol they're mostly just reducing the pop, decent on a rifle but you'll always be louder than the guy with a bigger stack.
Expectations-wise, I don't know if you've been around a silenced centerfire. Bigger bores are louder, supersonic rounds will still damage your hearing, and shorter barrels are louder. Adding a can to the end makes the rifle feel much heavier than doubling the weight of your scope or stock would, thanks Archimedes. That said with a Hybrid on my bench .223 I can comfortably shoot with light plugs. A friend has those NRR Bluetooth earbuds that clip out the gunshots and let him listen to NPR at the range, which is not comfortable when shooting a .308 with an 18" barrel unsuppressed. You will feel the benefit of reduced recoil and less pressure, especially if you're shooting from inside a blind or dense cover.
