I would go with a 416 weatherby or 460 wetherby
Yes that’s a good one. Same for the 416 Ruger.The .375 Ruger is a boring but effective choice. Offers a bit more pop than the H&H version with the same bullet weights. 260 Accubonds at 2900, 270 LRXs at 2800. Sounds good to me. Also, same case as .300 PRC.