I have two old Pacific single stage presses, one Dillon 550, and a Lee Loadmaster. I used to have a Hornady progressive, but sold it for lack of use. Nice press, but I like the setup on the Dillon and Lee better with the tool heads.
I use the 550 and the Loadmaster 90% of the time. The 550 does most of my high power hunting ammo and the Lee does anything high volume. The single stage presses get used to swag bullets, uniform primer pockets, and run small batches of test ammo when I don't want to setup the other presses for a new cartridge.
Every press that I've used has it's quirks. Once you know what they are, they all work well. My opinion, the Lee presses work fine. I've never had issues with mine for many thousand rounds of ammo. Yes, progressives are a lot faster, but take more time to setup. They aren't great for load development when you are changing charge weights, etc every 5 rounds or so.
Powder measures on the progressives is where I find the most annoyance. I don't like the Dillon setup as it's annoying to adjust, but it works the best with long grain powders. I like the simplicity of the Lee autodisc, but it is leaky with flake powder. I mostly use RCBS, Redding and Hornady measures with a case activated conversion for the progressive presses due to their ease of adjustment, but they are sticky with long grain powder. With ball powders they are sweet.
Jeremy