Peptides BPC-157 and TB-500. Shoulder pain

[mtbraun]

10mg on the nasal spray. Whatever the solution that its in has dried out my sinuses pretty bad though. Its been a month now using the nasal spray 4x a day. pain is pretty much gone, i think i can run a mile if i had to, but my achilles rupture is still very visible.

Now I am injecting BPC157 + TB500 locally near the tendon, subcutaneously. Just started last night. Will keep you all posted here.

Huberman has been saying that there is alot of anecdotal evidence of people healing themselves with BPC 157, including olympians. I am leaning towards snake oil at this point, at least for my injury, because my injury is still visibly there. Pain however is nearly gone so its doing something. I just hope this experimenting doesnt come at the cost of harm. Huberman himself has said its very safe. Either way, ill let you all know what i find.

I think the part of Olympians using BPC-157 is highly unlikely as it is on the WADA list. That assumes integrity in the process (sorry, my cynical self is overtaking).

 

[The Fat Coyote]

What dosages are you injecting of the BPC157/TB500 combo? The blends are confusing to me (specifically, does 500mcg of “blend” equate to 250mcg of each peptide?

Im closer to 330mcg. I weigh a bit more than most, so for my bodyweight i think 300mcg is what is usually recommended.

I’m curious how you guys are interpreting Huberman saying BPC157 is safe as it’s been placed on the do not compound list by the FDA? His last pod specifically on peptides basically messaged that because it’s on that list that he recommended staying away from the “grey/dark grey” market. I’m not arguing it’s efficacy but the way I interpreted it was that PDA was still allowed to be compounded and has the same result. Just curious if I’m absorbing old info.

This is true, the "dark grey market" really is dicey. This place i got it from, I'm just trusting them on faith that im not injecting saltwater into my skin. The website has good reviews however which put my mind at ease.

Day 2 of injecting BPC-157 and TB500 subcutaneously right next to my achilles- the swelling/rupture bump has gone down alot, this is really nuts, its probably 50% smaller. Still there however, and there is a dull ache, but the rupture looks to be smoothing out.

I am having a much better experience with the needle than the nasal spray. With the nasal spray i was finding it hard to wake up in the mornings, i felt like i needed more rest and my sinuses were drying out. With the injection, its a diabetic needle, it hardly hurts, just make sure all surfaces are clean. So far so good. I will keep you all posted.

 

[awcopeland]

The reasons for some peptides being blacklisted (like BPC-157) and others allowed is very unclear. Likely influenced by big pharma's attempts to create IP and/or some toxic stew they can shill to the uninformed.

To be clear, Huberman was speaking to the source of the peptide, not the efficacy. He's right in urging caution around "research" based suppliers. Also see Peter Attia and Craig Koniver for a good perspective on peptides from an actual clinician.

I'm hopeful under the new administration BPC and other useful peptides will be allowed to be compounded.

PDA and BPC-157 are both comprised of 15 amino acids, but their structure is different. PDA and CJC-1295 are two good alternatives to BPC-157.

Right. I’m not arguing the efficacy. It seems pretty clear, but finding a reliable source without the lipid polysaccharides is what seems to be the challenge

 

[Poser]

I'm giving it a try as I'm beat to shit right now. My doctor isn't much a believer, though there is a surgeon at my gym, super athletic guy pushing 60, who swears by it.

 

[TCUHunter34]

I’m not normally a person who takes supplements of any kind. I can count on one hand how many times a year I take any sort of pill, Advil, sleep medication, anything.

I haven’t had a single instance of knee pain since ~10th day of BPC 157 back in January from my original posts. I only took it for one month as again, I don’t typically take any sort of supplementation. I’m very happy with the results.

 

[philcox]

I’m not normally a person who takes supplements of any kind. I can count on one hand how many times a year I take any sort of pill, Advil, sleep medication, anything.

I haven’t had a single instance of knee pain since ~10th day of BPC 157 back in January from my original posts. I only took it for one month as again, I don’t typically take any sort of supplementation. I’m very happy with the results.

Was this the oral/capsule or do they sell an injectable version? Very curious of the efficacy of the oral ones.

 

[philcox]

I started BPC-157 from Apeirion Elementals less than 2 weeks ago. Nothing noticeable yet as I am fighting pretty severe knee pain. Awaiting an MRI to actually know the damage that’s been done. I’ll update this with any changes.

What is the injury you ended up having? I am dealing with degenerative torn meniscus, and am wondering if this is something that might help.

 

[TCUHunter34]

What is the injury you ended up having? I am dealing with degenerative torn meniscus, and am wondering if this is something that might help.

Definitely tendinitis at minimum, I had pain just while walking or even sitting at times. I have no idea if it will work for that or not.

It was in pill form.

 

[Poser]

What is the injury you ended up having? I am dealing with degenerative torn meniscus, and am wondering if this is something that might help.

People do commonly take it for that and that's one of the reasons I'm taking it as well.
I had one meniscus blow up on me about a year and a half ago. I was able to get it back to good working and pain free order (without BPC 157), but it was a long, slow process and there was already cartilage damage. Now, the other knee is showing similar symptoms.

I assume by degenerative, you have arthritis as a result? You'll get a wide range of opinions on this, ranging from "ride it out until you need a replacement" to "it is possible to grow some cartilage back."
Biggest factor I found was dietary -eat inflammatory foods and the inflamed joint is amplified. Beyond that, a combination of fish oil (omega 3), magnesium glycinate, boron, turmeric, boswellia extract, vitamin D, zinc and glucosamine, in the opinion of some, provide the right environment for regeneration. -that is a pretty cheap combination of supplements to take and potentially offers other benefits as well (magnesium, zinc, vitamin D and boron are common recommended supplements for testosterone support).


For this second round, I'm trying BPC 157 in addition to what is mentioned above. After my experience of going multiple rounds with doctors, PAs, surgeons, 3 rounds of X rays, MRI etc only to be told to "come back when it starts hurting bad enough that I need a knee replacement", I'm not wasting my time or money with any of that. Of course, that's me and that's probably terrible advice.

 

[philcox]

People do commonly take it for that and that's one of the reasons I'm taking it as well.
I had one meniscus blow up on me about a year and a half ago. I was able to get it back to good working and pain free order (without BPC 157), but it was a long, slow process and there was already cartilage damage. Now, the other knee is showing similar symptoms.

I assume by degenerative, you have arthritis as a result? You'll get a wide range of opinions on this, ranging from "ride it out until you need a replacement" to "it is possible to grow some cartilage back."
Biggest factor I found was dietary -eat inflammatory foods and the inflamed joint is amplified. Beyond that, a combination of fish oil (omega 3), magnesium glycinate, boron, turmeric, boswellia extract, vitamin D, zinc and glucosamine, in the opinion of some, provide the right environment for regeneration. -that is a pretty cheap combination of supplements to take and potentially offers other benefits as well (magnesium, zinc, vitamin D and boron are common recommended supplements for testosterone support).


For this second round, I'm trying BPC 157 in addition to what is mentioned above. After my experience of going multiple rounds with doctors, PAs, surgeons, 3 rounds of X rays, MRI etc only to be told to "come back when it starts hurting bad enough that I need a knee replacement", I'm not wasting my time or money with any of that. Of course, that's me and that's probably terrible advice.

I’ll check this out. Yes by degenerative I mean that basically I’m wearing them out. I’m 60 years old, and I’ve just done a lot of stuff on my knees, and the tears happened, and pain is always there at some level. Stiffness in AM. I have done a bunch of the knees over toes guy protocol, and I like that for strengthening, and getting things set up around my meniscus, but thought maybe trying to help the cartilage out at some point would be useful as well. For the BBC 157, are you goin pill form or subcutaneous?


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[philcox]

@The Fat Coyote I'd love to get an update. This would now be a couple months down the road for you. I am really curious as to progress to this point. Hope you can update this thread.

 

[Poser]

For the BBC 157, are you goin pill form or subcutaneous?


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Everything I've read is that the injections work best, however, the surgeon I frequently speak to at my gym said that he had been reading positive data on some of the newer generation capsules. Apparently, they employ some type of sodium compound that potentially allows for absorption. I'm not scared of needles at all, but I feel weird about giving myself injections so I'm trying the capsules first: https://infiniwell.com/products/bpc-157-rapid-pro

The surgeon I speak to would not go so far as to conversationally recommend any particular brand, but I did some research on what he said and came across multiple Reddit threads that pointed to the capsules linked above. That is as far as I've gotten, but will report back in a couple of weeks. In addition to knees, I have an injured rotator cuff (snowboarding), ongoing issues with inflamed elbows (ski poling really lights them up) and a jammed thumb that is swollen up twice the size of the other thumb from a skateboard crash....