I will admit I did not read through all the pages on this but it is something I've been debating myself. Right now, by the way, I shoot a 6.5 PRC with 147 grain DRTs
They are not making the 147 grain anymore who knows if they ever will again...
I also know that all of their products are out of stock and that concerns me a bit.
I would love to make a 6 Mill creedmoor. For out to 500 it would absolutely be a wonderful caliber for killing all sized game but DRT only makes a 95 grain bullet and I'm concerned with that weight. Maybe
@Formidilosus has some thoughts on that.
If we're looking at a one and done type scenario it's really tough to beat the 6.5 creedmoor IMO with the right bullet such as the 135 grain DRT if it gets back in stock anytime soon. Simply bc of the vast number of rifles and manufacturers.
Also if we are not to see much more of the DRT ammunition (which would be a true disappointment) you might look at Maker's bullets as their design seems to expand significantly even for the standard mushroom bullet type, with a larger expansion character vs similar style of monolithic bullets.
Cheers and good luck!