Diamondback
FNG
To mirror what others have posted on accuracy and shot placement, this is a nice article from Alaska Fish and Game website on calibers:
www.adfg.alaska.gov
Firearms and Ammunition
How accurately you shoot is far more important than the type of rifle, cartridge, and bullet you choose. Alaska has some very large game animals, including 1600-pound mature bull moose and 1500-pound coastal brown bears. Moose or brown bear hit in the gut with a large caliber magnum rifle such as the popular .338 Winchester Magnum is wounded and just as likely to escape as if it had been hit with a small caliber rifle such as the .243 Winchester. The bore size, bullet weight, and velocity are of secondary importance to precise bullet placement in the vital heart-lung area.
To be as effective as possible, these cartridges should be loaded with premium quality bullets that are designed to pass completely through a large game animal, if hit in the heart-lung area. (penetrate vitals)
Big Magnums not Needed:
The rifle you bring Hunting should be one with which you are comfortable. Because of the presence of brown and grizzly bears, many hunters have been convinced that a .300, .338, .375, or .416 magnum is needed for personal protection and to take large Alaska game. This is simply not true.
The two most common complaints of professional Alaska guides are:
1. hunters who are not in physical condition
2. hunter who cannot accurately shoot their rifles
Most experienced guides prefer that a hunter come to camp with a .270 Win or 30-06 rifle they can shoot well rather than a shiny new magnum that has been fired just enough to get sighted in.
Since a 6.5 PRC has higher BC premium bullets than a 270 Win at higher velocity and it recoils less than a 30-06, it fits right into what Alaska Fish and Game website has posted online.

Firearms and Ammunition for Hunting in Alaska, Alaska Department of Fish and Game
Information on hunting and trapping in Alaska.
Firearms and Ammunition
How accurately you shoot is far more important than the type of rifle, cartridge, and bullet you choose. Alaska has some very large game animals, including 1600-pound mature bull moose and 1500-pound coastal brown bears. Moose or brown bear hit in the gut with a large caliber magnum rifle such as the popular .338 Winchester Magnum is wounded and just as likely to escape as if it had been hit with a small caliber rifle such as the .243 Winchester. The bore size, bullet weight, and velocity are of secondary importance to precise bullet placement in the vital heart-lung area.
To be as effective as possible, these cartridges should be loaded with premium quality bullets that are designed to pass completely through a large game animal, if hit in the heart-lung area. (penetrate vitals)
Big Magnums not Needed:
The rifle you bring Hunting should be one with which you are comfortable. Because of the presence of brown and grizzly bears, many hunters have been convinced that a .300, .338, .375, or .416 magnum is needed for personal protection and to take large Alaska game. This is simply not true.
The two most common complaints of professional Alaska guides are:
1. hunters who are not in physical condition
2. hunter who cannot accurately shoot their rifles
Most experienced guides prefer that a hunter come to camp with a .270 Win or 30-06 rifle they can shoot well rather than a shiny new magnum that has been fired just enough to get sighted in.
Since a 6.5 PRC has higher BC premium bullets than a 270 Win at higher velocity and it recoils less than a 30-06, it fits right into what Alaska Fish and Game website has posted online.