I can't recommend shooting deer or hogs with subsonic 300 black outside of headshots.
I'm in Texas and have participated in field dressing/processing 4 dozen+ animals that were shot with 300 black. The 3 bullets I've got experience with are the nosler 125gr ballistic tip, barnes 110gr black tip, and hornadys 190gr sub-x.
The barnes at supersonic velocities opens reliably and has left a gorgeous blood trail if the animal moved at all. I've personally shot 6 hogs this year alone with this bullet. Phenomenal results.
The nosler at supersonic velocities has expanded violently, usually causing the loss of shoulder meat from 1 or both shoulders. Bullet performes like you'd expect. I'll admit, I've only seen a few animals killed with this bullet.
The 190gr sub-x. Where do I start... Hornady has some really good marketing around how this bullet performs. Sometimes (20%) it lives up to the hype. The rest of the time (80%) it doesn't. The problem with sub sonic bullets is that when/if they expand, they rarely have any sort of "explosive" expansion to them (minimal temporal cavity) and this particular bullet does not have the ability to create large cutting petals (like the barnes). So even with perfect bullet performance the internal damage looks a lot like something shot with a field point from a bow, or maybe just better than that. For me, in thick south texas brush its a no go, and officially off the list of approved cartridge/bullet combinations. I've seen several animals hit well (saw bullet impact on the animal as a spotter) that weren't recovered until the birds showed us where the animal died.
On your question, suppress whatever rifle you want to hunt with. Once you're shooting supersonic there's not a big reason to use 300 black unless there is a compelling reason to use an AR platform