I did the Nomad thing even with a "camp bag" of silnylon. Just finished my first trip with the EMR II and I won't go back. Even though I didn't have to pack anything out, the EMR II was fantastic as a day pack, better than when I used the Nomad without a center bag. Those little pockets on the front of the EMRII are quite handy. Granted, I carry more crap (camera gear) than most folks might but it was nice to have both those pockets and even the main bag for smaller stuff. I should have taken photos of my typical daily loadout but I will try to do that some other day. Overall, I was very impressed at how small it could compress down for hunts out of a base camp yet I was confident that I could carry a whole load at any moment if needed.
To me, the thing with the Nomad is the fact that you can drop you camp bag and have a nice day pack. However, if you need to be prepared to pack an animal at a moment's notice, you would still have to carry some sort of camp bag or meat bag or whatever with the Nomad so weight savings are negligible. Still, the Nomad is a great option if it works for you. For me, I plan to use the EMR II primarily and I have a Highcamp 7000 that I plan to modify for a lightweight option should that ever really be needed.