7mm08, 131gr hammer hunters, loaded over Varget at ~3015 fps.
I shot an antelope at 265yd broadside in October - baseball sized exit hole, massive damage to chest cavity. Surprised to see it run 40-50 yards but it was clearly dead before it knew it..
Update from my elk hunt last week - shot a cow in the neck, facing me directly at 70 yards in its bed. It never got to its feet, it immediately slumped over. I didnt closely investigate the damage track but saw that it entered in the 'open space' into the chest cavity and passed between heart and lungs, rupturing the aorta. It ended somewhere in the guts, I didn't explore further

Best part - no meat damage whatsoever!
These shoot really well for me (0.5 MOA) and perform well on game. I'm a fan!