You have alot of great 'how to go about it' answers here, but I didn't see anyone chime in with the answer to your questions on frequency.
The central idea would be twice a week per muscle group. The best bang-for-your buck/ROI on time would be compound movements as you're able to work multiple groups in a single movement. It could be a really great investment in your time to hire someone to show you how to do those movements properly if you're new to them.
Some other food for thought:
- "Cardio on the menu 5x/week" will conflict with strength (to a point). You can enjoy the honeymoon of having progress with both if you’re brand new to strength training!
- Complete execution of the lift with good form will ALWAYS beat the amount of weight being moved. Something I have to often remind myself of is "form > ego".
- You do not 'need' any supplements if you follow 4 &5.
- Eat the amount of fuel needed to achieve your bigger goal.
- Eat the amount of protein you need to facilitate recovery from your efforts.
Enjoy it. It truly can be a marvel at what we're capable of. I look forward to hearing about your progress.