Not trash talking but I'd think you'd be chasing a single digit SD with your setup.It depends what your goal is and what ranges you'll be shooting.
If you're 500 yards and under, an ES of 50 won't matter at all. That's plus or minus 25 fps, which equates to less than an inch difference (my rifle / load) at 500 yards.
At 1000 Yards, that grows to ~6" of vertical dispersion. And continues to go up from there.
Personally, I'm chasing ES in the teens for all my loads because I like tweaking for the "best" load possible.