Did it make the jump?

Reburn

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At what rate can a false negative come through? Would a false negative only present if the animal recently contracted the illness and doesn't have a plethora of prions? Or is the test faulty in a way even a sick animal can throw a false negative?

Not sure you know the answers, just asking for discussions sake. I know WY G and F claim 99.98 percent accurate (or something along those lines). So is it a .02% chance of a false negative?

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I don't have those numbers and I dont think anyone really knows about what the true percentage of false negatives vs actual positives are. The only way is #1 to run a live test, node test and stem test on a deer known negative and more importantly #2 a known positive in sufficent sample size to be able to determine a accurate percentages.

The cervidae industry has identified genetic markers in whitetail that indicates an animal will be immune or resistant to CWD and breeders are selectively breeding for those genetics. In the wild deer selectively breed by attrition which just takes longer for a local population to become CWD resistant.

I do know for fact that there have been some captive deer herds have a positive test come back either live or post mortem and the entire herd be destroyed and all brain stems tested and not 1 positive test come back other then the initial test.
 
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Stalker69

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It’s interesting for sure. CJD is pretty rare..probably not a coincidence that these two guys both died from it. I am not aware of any reason CWD CANT infect a human. Hasnt been proven yet, but it would be fairly difficult and logistically impossible to prove conclusively that it can’t infect humans. My personal belief is that people have probably died from CWD and it is attributed to something else. Not every 60 year old guy that dies gets an autopsy. Lots of small hospitals out there that people die in.

That being said I know I am more likely to die driving to and from hunting, and probably by lightening or a grizz…but I’ll get my deer tested in endemic areas for peace of mind.
When my mother and father in law passed away, both times we asked if they could check for CWD at the time of the autopsy both times, they had no clue what we were talking about. And we’re told there is no test.
 

grfox92

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When my mother and father in law passed away, both times we asked if they could check for CWD at the time of the autopsy both times, they had no clue what we were talking about. And we’re told there is no test.
Did they both display signs of cognitive decline?

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I’m fairly cautious about CWD, getting every deer I kill tested, butchering the meat myself, and not eating any of it until results come back. I also avoid hunting the 1 part of my state that has a really high prevalence rate, because I don’t want to go through all that work just to find out the deer was positive.
Arkansas has CWD drop off locations in every county where you can take the heads, and pretty much any taxidermist is equipped to send in samples. If you kill an elk, it’s actually required to take it in-person to get tested, but for deer it’s just a recommendation.
All that being said, two close friends getting CWD is enough of a coincidence that it has me concerned, but it’s far from a smoking gun.
 
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Here's an article debunking the original claims.

“After speaking with [one of the authors] Dr. Sarah Horn, she informed us that the information is not from a research study, it was a poster presentation of a case report presented at the AAN annual meeting,” UT Health San Antonio public and media relations specialist Eileen Teves tells Outdoor Life in an email statement.

"The authors — three of whom are doctors of neurology and one an MD candidate at the University of Texas San Antonio Long School of Medicine"

I figured. A medical student who stretched the truth a little too far to make his case study more flashy. And Sarah Horn was the person in charge, she should have made him rewrite that abstract.
 

UncleBone

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As much of shotty "journalism" that makes it, it doesn't surprise me this is a trending search on google.
Screenshot_20240419_110644_Samsung Internet.jpg
 

chindits

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With words like: hinting at potential and understand this possible association

It’s only the medical experts at the University of Rokslide that are making assertions, excuses and pointing fingers.


“hinting at potential cross-species prion transmission. Surveillance and further research are essential to better understand this possible association.”
 
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With words like: hinting at potential and understand this possible association

It’s only the medical experts at the University of Rock Slide that are making assertions, excuses and pointing fingers.
You don't know what anyone here does for a living. And if they didn't screw up their framing/wording, this wouldn't have been noticed at all. Let alone all over the news. But they did, so now actual scientists are having to come out and calm people down.
 
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“After speaking with [one of the authors] Dr. Sarah Horn, she informed us that the information is not from a research study, it was a poster presentation of a case report presented at the AAN annual meeting,” UT Health San Antonio public and media relations specialist Eileen Teves tells Outdoor Life in an email statement.

"The authors — three of whom are doctors of neurology and one an MD candidate at the University of Texas San Antonio Long School of Medicine"

I figured. A medical student who stretched the truth a little too far to make his case study more flashy. And Sarah Horn was the person in charge, she should have made him rewrite that abstract.
Here’s how these things work. Ambitious medical student asks attending to help them get involved in a publication. Busy attending says here write up a case report on this rare/interesting/whatever case. I don’t have time to do it myself. Medical student writes it, attending etc edit it..and it’s submitted.

Case reports are very low level “evidence”. Nobody in their right mind changes how they practice medicine or what science they believe based on a case report.

But case reports might lead to someone else interested in the idea who goes further and maybe does “real” research.

A few “real” research papers might lead to something larger or robust and maybe someday CWD transmission could be rigorously studied.

I have a handful of potential case reports but I am too lazy to write them up myself…but an ambitious intern is working on it for me ha.

Not sure where stretching the truth comes in..obviously the media has run with this one.

A case report is pretty much “cool story bro” in the world of medicine. The media is retarded but obviously free to do what it wants. The whole situation/coincidence is very interesting and nothing more. Do with the information what you like.
 

Johnny Tyndall

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MT
I have meat in my freezer for 5-6 years. double wrapped. Not freezer burnt at all.
You think any prion is surviving ???
Yes. Prions aren't actually alive, they are just proteins. Freezing is generally how you preserve them. It's heat that wrecks them, not cold (I do not know how hot you need to get a CWD prion to deactivate it).
 
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attending etc edit it
The attending should have edited the abstract. It is saying something that is unproven and obviously has caused alarm. That's one of my main points.
I have a handful of potential case reports but I am too lazy to write them up myself…but an ambitious intern is working on it for me ha.
And I'm sure since you're responsible, you'll be editing them so that people don't panic or draw conclusions from them that aren't supported by the substance of the report.
Not sure where stretching the truth comes in..obviously the media has run with this one.
I'll paste the quote from the abstract that is unproven and irresponsible. Coincidentally, it's what most people are freaking out about.

"This study presents a cluster of Creutzfeldt-Jakob disease (CJD) cases after exposure to chronic wasting disease (CWD)-infected deer"

There is no proof they were exposed to CWD-infected deer. Full stop.
Here’s how these things work.
I'm very aware how these things work. Having had to work with MDs on multiple "real" research papers, as you say.
 
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The attending should have edited the abstract. It is saying something that is unproven and obviously has caused alarm. That's one of my main points.

And I'm sure since you're responsible, you'll be editing them so that people don't panic or draw conclusions from them that aren't supported by the substance of the report.

I'll paste the quote from the abstract that is unproven and irresponsible. Coincidentally, it's what most people are freaking out about.

"This study presents a cluster of Creutzfeldt-Jakob disease (CJD) cases after exposure to chronic wasting disease (CWD)-infected deer"

There is no proof they were exposed to CWD-infected deer. Full stop.

I'm very aware how these things work. Having had to work with MDs on multiple "real" research papers, as you say.
You’ve investigated and found that information to be false?

People can choose to be alarmed or not. I post my opinions, just like everyone else on this site. I don’t have strong emotions about CWD. I’ll watch all this play out over my lifetime and will try to avoid eating a CWD deer. I won’t lose any sleep over it.

I also wore my mask at work during Covid, even though I knew my chances of dying from it were close to zero.

As you know science and medicine can be wrong, misleading, and a lot of times also correct. I don’t know anything about this particular journal but there is a load of “junk” research out there. Facts change over time. I take in the data and go from there.

Two deer hunters in an endemic area die of CJD…those are the facts and that is what I take away from the case report.
 
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