I finally have one small data point for this thread
My lady killed her first deer this weekend, a button buck about the size of large dog.
.243 100gr Norma softpoint. 50yd shot, deer traveled about 50yd after the shot. The deer appeared broadside, but was quartered away.
Shot entered behind the near side shoulder and exited forward of the offside shoulder.
Caliber size entry, pingpong ball size exit. Lung material was blown out of the exit. She took out the top of the heart, but I didn't do much of a necropsy. No fragments were found during butchery.