Funny story. When I was 16 my father bought me a new rifle to replace my youth model 243 because it was too small. I insisted I wanted a 300 Wby Mag because it was the flattest shooting thing at the time (I'm 50) that I knew of. He bought it and we sighted it in and went to the lease. My buddy was super excited and kept egging me on to shoot literally anything and everything with it. Walking along looking for hogs in bedding areas a jackrabbit popped out into view about 60 yards out. Buddy went nuts, to the point I was annoyed with him. Holding my rifle sidearmed I flipped the safety off and fired from the hip not intending to actually connect. Rabbit literally exploded, pieces went everywhere and some guts were scattered in trees. All we found was a small section of hind leg and golf ball sized chunks everywhere. We went back to camp and buddy is losing his mind telling my father all about it. Dad didn't believe us so out we went now looking for rabbits. He kept making me shoot the dang things and it kept just penciling a caliber sized hole in every one of them and they'd run around and fall over dead. I finally told him we lied about it (we didn't) just so I could stop shooting rabbits and he said he hoped I learned my lesson.I know a guy who shot a jackrabbit with a 460 Wby Mag.
Bunny ran off. Died pretty quick but it ran off.
So yeah, the whole prairie dog thing is a pretty ridiculous comparison to try to use to claim a bullet isn't good for larger animals.
