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EDIT:: sorry I forgot CO won't let you use sabots. I would try the ELD-X or full size Thor, Fury, or no excuses. The Eld-x also shot well for me and seems to be working for others.
I’ll give you a run down on my experience last year. I had my first muzzleloader elk hunt here in Nevada. I choose the Barnes 290 tmz bullet to start with due to it being a tough bullet that would have good penetration. I ended up testing different loads and settled on 95 grain of BH209 by volume. This shot well out of my Thompson Center, but every gun will be different.
I practiced a few times a month all summer and was able to group about 3” at 200 yards with open sights. I shot my bull at 190 yards quartering towards and he ran back about 30 yards and stopped while I was reloading. This bullet went through both shoulder blades at 230 yards and was about 1” under the skin in the far shoulder. He dropped straight down after this second shot. I was very happy with the performance of this load and bullet.