TRT

[PredatorSlayer]

23ga 1” in my thigh has been my go to when I do it myself.

 

[Long Cut]

There us a whole "Sub Q- daily inject" clan vs "IM weekly" clan. Daily would seem like a PITA (get it?) to me.

I didn't see or feel too much up and down w once weekly.

I’ve done both, 1x week and now every 3rd day.
Same dosage of 1cc 200mg Test Cyp weekly with 800mg daily DIM for Estrogen blocking.

At 1x week I averaged around 650’s Total Test. At 2x week I’m right at 950-1,000 Total Test.

Everybody is different, whatever works best for your situation, roll with it.

* These blood labs are drawn the day I inject. So blood labs at 0800 and I’ll inject later that day.*

 

[KsRancher]

Anyone have experience with the pellet implant? My wife is 38yrs old and had a full hysterectomy 2yrs ago. Been a very rough 2 yrs. The Dr recommended a "Bio-T" pellet. She got it a little over 2 months ago. WOW...... not the same woman.


The brochure my wife brought home before getting the implant said they have it for men also. It's a once every 3 or 4 month thing.

 

[Marble]

What a Pussy....really?

Relax- this is sarcasm. As a self admitted needle phobe- this was my goal. I am a Numbers Guy. And when I can see down the hole inside of a needle...that was about my threshold.

Would take me several beers to run an 18g injection.

25 - 1.5" was my standard and got to be mainstream over time. I ran a handful of 23g just to make sure I could do it and overcome some anxiety.

I would inject anywhere from hip flexor to my quad. Hit a lot of nerves over the years. And I would generally inject the syringe to the balls (plastic).

Probably much better technique and locations. I couldn't rotate my torso to hit my own glutes. So I ran where I could reach.

I don't ever recall an issue "waiting forever" to push 120/140 with a 25g. Seemed easy enough.

Daily cream is soooo much easier.

My Spanish is pretty good. But still felt like an addict trying to communicate with a hospital in Cozumel asking them for a syringe to inject testosterone while on vacation. Was sketch enough entering the country w a vial in my carry one. Cream is so much more simple.

I coulda hit all sorts of Deca and Winstrol while I was there for just a couple bucks tho........

I've been using the mirror and pinning my butt since 2014. Don't think I've ever have had an issue.

And I travel internationally several times a year a no one has ever said anything. Have they said something to you?

It is a lot of personal preference. Doesn't seem to bother me.

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[Marble]

Anyone have experience with the pellet implant? My wife is 38yrs old and had a full hysterectomy 2yrs ago. Been a very rough 2 yrs. The Dr recommended a "Bio-T" pellet. She got it a little over 2 months ago. WOW...... not the same woman.


The brochure my wife brought home before getting the implant said they have it for men also. It's a once every 3 or 4 month thing.

IME, there is a big swing from the initial dosage goes in to when the new pellet goes in. The injections are convenient, particularly for travel, and usually painless. I can also inject twice weekly and keep my levels more stable.

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[Jesse Jaymes]

I’ve done both, 1x week and now every 3rd day.
Same dosage of 1cc 200mg Test Cyp weekly with 800mg daily DIM for Estrogen blocking.

At 1x week I averaged around 650’s Total Test. At 2x week I’m right at 950-1,000 Total Test.

Everybody is different, whatever works best for your situation, roll with it.

* These blood labs are drawn the day I inject. So blood labs at 0800 and I’ll inject later that day.*

Any insight on DIM? A co-worker turned me onto it. My Hormone DR said kinda 50/50 if it works. I do take it daily. Capsule. I do think it's helped out my ratio Est/Test quite a bit.

RE: Women's hormones. At 53 and my wife just a few month ahead of me....I would suggest getting your wife in BEFORE you consider yourself. My wife is terrible about taking her hormone meds, but it's been nearly a game changer for menopause and life together.

Possibly the best investment for a marriage when you get this age.

 

[Marble]

Any insight on DIM? A co-worker turned me onto it. My Hormone DR said kinda 50/50 if it works. I do take it daily. Capsule. I do think it's helped out my ratio Est/Test quite a bit.

RE: Women's hormones. At 53 and my wife just a few month ahead of me....I would suggest getting your wife in BEFORE you consider yourself. My wife is terrible about taking her hormone meds, but it's been nearly a game changer for menopause and life together.

Possibly the best investment for a marriage when you get this age.

The stuff my dr gave worked. My estrogen was at 36, which i dont know what is supposed to be at. First time it was high ever in 10+ years. I took the DIM therapy for a month and it was lowered significantly.

I would only worry about it if the levels get too high.

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[PredatorSlayer]

Anyone have experience with the pellet implant? My wife is 38yrs old and had a full hysterectomy 2yrs ago. Been a very rough 2 yrs. The Dr recommended a "Bio-T" pellet. She got it a little over 2 months ago. WOW...... not the same woman.


The brochure my wife brought home before getting the implant said they have it for men also. It's a once every 3 or 4 month thing.

My buddy and his wife both use pellets. Heard it is harder to dial in.

 

[KsRancher]

Any insight on DIM? A co-worker turned me onto it. My Hormone DR said kinda 50/50 if it works. I do take it daily. Capsule. I do think it's helped out my ratio Est/Test quite a bit.

RE: Women's hormones. At 53 and my wife just a few month ahead of me....I would suggest getting your wife in BEFORE you consider yourself. My wife is terrible about taking her hormone meds, but it's been nearly a game changer for menopause and life together.

Possibly the best investment for a marriage when you get this age.

Hands down the best money I have ever spent. I mean it's not even the same woman. From mood, energy, sexually and everything else. At 38yrs old she be-bops like she did at 18yrs old.

 

[Team4LongGun]

Has anyone had a bad reaction to TRT injections? I had 2 separate and severe reactions. One led to ER visit.
Both occurred about 5 days after injection. RHR was 130 (should be 57-65) sitting down, high fever out of
nowhere.

Had blood test to check for allergy to delivery oil, nothing came back.

 

[PredatorSlayer]

Has anyone had a bad reaction to TRT injections? I had 2 separate and severe reactions. One led to ER visit.
Both occurred about 5 days after injection. RHR was 130 (should be 57-65) sitting down, high fever out of
nowhere.

Had blood test to check for allergy to delivery oil, nothing came back.

No reaction for me…you doing IM or subq?

 

[BadDogPSD]

Has anyone had a bad reaction to TRT injections? I had 2 separate and severe reactions. One led to ER visit.
Both occurred about 5 days after injection. RHR was 130 (should be 57-65) sitting down, high fever out of
nowhere.

Had blood test to check for allergy to delivery oil, nothing came back.

No, no reactions like this.

 

[Loco4dux]

Anyone ever take clomid to increase testosterone production and preserve fertility with success?

 

[sandhillhunter]

I’ve been listening to Dr. Peter Attia recently. He has some really good, detailed discussions on health and longevity issues.

This recent podcast covers quite a bit about hormone therapy (and fertility).

Most of the hormone discussion starts around the 1 hour mark.

They also discuss my question about blood clot risk and TRT. Apparently, the old doses of 200 mg every 2 weeks caused polycythemia (high RBC counts) which can predispose you to clots.

Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Podcast Episode · The Peter Attia Drive · 06/02/2025 · 2h 19m

podcasts.apple.com

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[bowhuntercoop]

Anyone ever take clomid to increase testosterone production and preserve fertility with success?

Enclo is awesome as a pct to boost natural test, very common in the supplement / body building / sarms world.

Clomid has some nasty sides for a lot of dudes and most would recommend enclo over it, unless you’re taking legit steroids I don’t see the need imo.

 

[Long Cut]

Any insight on DIM? A co-worker turned me onto it. My Hormone DR said kinda 50/50 if it works. I do take it daily. Capsule. I do think it's helped out my ratio Est/Test quite a bit.

RE: Women's hormones. At 53 and my wife just a few month ahead of me....I would suggest getting your wife in BEFORE you consider yourself. My wife is terrible about taking her hormone meds, but it's been nearly a game changer for menopause and life together.

Possibly the best investment for a marriage when you get this age.

I’ve been using DIM for ~2 years now, took 1mg Anastroloze weekly for 1 year prior to DIM.

My PCP referred me to DIM and took me off the Anastroloze my previous clinic had me on.

That being said, I convert heavily to Estrogen for some reason. Think 90+ range. Taking 400mg DIM daily had me around 60-70 range. 800mg DIM has me down in the 40-50’s, which is perfect for me.

 

[Jesse Jaymes]

I’ve been using DIM for ~2 years now, took 1mg Anastroloze weekly for 1 year prior to DIM.

My PCP referred me to DIM and took me off the Anastroloze my previous clinic had me on.

That being said, I convert heavily to Estrogen for some reason. Think 90+ range. Taking 400mg DIM daily had me around 60-70 range. 800mg DIM has me down in the 40-50’s, which is perfect for me.

Anastrozole was bad ju-ju. Shit REALLY fukt with my mood and hormones. I would strongly recommend against it for newbies, or ask for alternate means.

 

[Marble]

Anyone ever take clomid to increase testosterone production and preserve fertility with success?

You can take HCG to help with that. Either by prescription or you can find it lots of places on the internet.

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[Mangata]

Have done BioTe with good results within reason. Really nice to have pellets inserted twice a year is certainly a pro. Cons can be difficulty dialing dose for reasonable peak levels (usually ended up on the higher side which yields polycythemia and need to dump blood), as well as testicular atrophy (going to happen with exogenous testosterone no matter what)
Currently using Clomid & Anastrozole a couple of times a week which seems to keep hormone levels good without polycythemia, and as well doesn’t yield testicular atrophy. I haven’t noted any real side effects with my current regimen.
YMMV, check with your doctor for which hormone replacement therapy is most appropriate for you. Be informed and be safe; medicine is not a cut and paste cookie cutter solution where one size fits all…

 

[*zap*]