Not arguing that fact, but I'd still buy the 280 Ackley if I were to just have one rifle. Has a less recoil than a magnum but still plenty of power for hunting large game. More rifles are being chambered in it so ammo isn't as hard to come by like it used to. Plus I doubt it happens as most people think about loosing their ammo and ruining a hunt. I admit there can be a slight chance if dealing with airlines, but the majority of people will never have that issue.
Just my personal choice if going with a single rifle, but since I didn't & the OP doesn't plan too, it's why I voted for the 270 & 300wm.