That's not how this works
If you buy $10,000 of VTI from Vanguard, Vanguard goes into the market and buys $550 of nvidia, $600 of Microsoft,..., $160 of tesla, ...., and also $16 of MSTR.
[Well the actual mechanics of etf share creation are more complex and work via in kind redemption/provision by brokers but the above is mostly correct]
You don't get to pick what VTI invests in. You don't get to select or exclude. It's just tracking an index.
You can actually check which funds run by Vanguard are holding MSTR. the biggest is VTIX which just tracks the whole US market