Mighty Mouse
WKR
+1 for Guadalupe Mountains and Big Bend NP's. I visited them many times when I lived in Midland.
Arizona Snowbowl near Flagstaff if you're into skiing and the conditions are good.
These next suggestions may be too far north of your intended route, but if you do swing up toward the Four Corners area, Chaco Canyon and Canyon de Chelly are worthwhile stops if Native American history interests you. Antelope Canyon and Horseshoe Bend overlook are worth a stop if you're near Page, AZ.
Arizona Snowbowl near Flagstaff if you're into skiing and the conditions are good.
These next suggestions may be too far north of your intended route, but if you do swing up toward the Four Corners area, Chaco Canyon and Canyon de Chelly are worthwhile stops if Native American history interests you. Antelope Canyon and Horseshoe Bend overlook are worth a stop if you're near Page, AZ.