What brass are you running that is so terrible, that it won't allow your rifle to shoot a decent group?
I've got 5x fired on a batch of 50pc. Norma brass reserved for 130 HVLDs. Trim to min. length & anneal after 3x fired, they are shooting incredibly well.
As for the 130 HVLDs, I found a load quickly, using standard procedure. Seat bullet into the lands, ladder test w/ chrono to find pressure & velocity performance. Things looked promising, so did some group testing and picked the one with the least vertical at distance. This stuff is only as hard as you wanna make it...
A bullet/powder is either gonna shoot, or it ain't. By the time you ladder test, you will have a real good indication of accuracy potential, and hard data for velocity. If either one is lacking, don't make excuses! Excuses aren't going to magically make a load start shooting, so MOVE ALONG and find something your rifle likes...
The 6.5 SAUM is not so inherently finicky that a good load can't be found for it. Assuming you've got a soundly built rifle there, IMHO, you just haven't found a good load yet. Mainly because you seem so dead set on trying to make a (Matrix) bullet shoot, that just don't wanna shoot. It happens, don't be upset. Just MOVE ALONG and find happiness somewhere else...
Seems like you had your heart set on using those Matrix bullets, and throated your chamber specifically for them. But, as evidenced by your frustration in this thread, they just ain't wanting to shoot.
So, instead of blaming "brass softness", "powder lot" or any other of the excuses you've speculated about in this thread, MOVE ALONG and try a different bullet and/or powder combo. Berger, JLK, Amax, Nosler, Scenar...pick a bullet and start over.
To be blunt, I think that long throat/Matrix bullet tangent you went off on, is coming back to bite you in the azz. GAP spec'ed their 6.5 SAUM 4s reamer based on LOTS of field data & testing with different bullet styles. Subsequent to the release of their version of the 6.5SAUM, there's been many happy shooters who've either had GAP build a rifle, or who've used the GAP 4s reamer design to build their own rifle (like me).
Reading back through this thread reminds me of someone trying to pound a square peg, into a round hole. Don't blame the peg for not fitting, find the one that fits & use it!