Yes it can matter, but the difference is not as much as most people would like to think. Improvement is only about 20 - 25%, and not all load combinations show an improvement. It's not for everyone because it takes a lot of shooting to prove that small of a difference. That's also why some people think it doesn't matter. They aren't shooting enough to disprove it. It takes statistically significant sample sizes from multiple rifle/load combinations to come to a definite conclusion. Not many people are doing that much testing.