I load for a couple different CMs (not Rugers though) and use h4350 in bullets 125+ and h4895 for the 120s. In both cases, they aren’t the fastest powders but they shoot really well.
For deer and coyotes I would probably go with a 120 nosler bt and a moderate charge of h4895 for accuracy. If you want a few more fps, work up to a max load of h4350.