Other folks may have different experience, but I didn't find the spine consistency of the RIP TKOs to be as good as some other arrows I've used. I'd personally go with the stiffer spine. The 300s are 0.1 gpi difference in weight, so it's not like you're paying a big weight penalty for going with the stiffer spine.
Victory has done some amazing work with that shaft with the spine to weight ratio. Probably the best hunting shaft on the market in that regards. Also very durable. Components are crap, but that is typical for .204s.