Peptides BPC-157 and TB-500. Shoulder pain

[The Fat Coyote]

@The Fat Coyote care to share what brand you are using?

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I ordered from directhealthshop.com - i didn't mention earlier because i didn't want to sound like a schill for a peptide shop. its really hard to discern which places are legit and which ones are riding a hype train.

they're a bit pricier than other online shops but they sell everything you would need so i picked them out of convenience more than anything, their reviews are decent as well.

 

[timekiller13]

Man I don't feel like injecting myself daily, any other options?

There’s a nasal spray for BPC-157. Its molecular weight allows it to absorbed through the mucous membranes. It’s the only one that can be administered that way, that I’m aware of.

Amino Asylum has it available from time to time.

 

[earrow]

I did the ipamorelin regimen twice a couple years ago would do it again, but I don’t think it’s available better sleep less pain more energy better sleep was probably the most noticeable not tired in the middle of the day did the blood work I think it helped with the HGH level don’t remember for sure

 

[180ls1]

Look into PRP as well, I would try this before the peptides as they may have an interference effect.

 

[awcopeland]

OP, have you talked to a physical therapist about your shoulder pain? I was having some pain in my release hand, talked to a PT, and got some relief doing some stretching and some banded exercises mostly focusing on external rotation strength and Lat. Dorsi strength.

The stretches I've done are whats called a Sleeper Stretch and also a basic stretch for the bicep using a doorway or wall to hold onto.

Peptides have piqued my interest as well, but I'm not one to experiment with my health and after listening to the Huberman podcast, I'm in no rush to seek peptide use.

 

[mtbraun]

OP, have you talked to a physical therapist about your shoulder pain? I was having some pain in my release hand, talked to a PT, and got some relief doing some stretching and some banded exercises mostly focusing on external rotation strength and Lat. Dorsi strength.

The stretches I've done are whats called a Sleeper Stretch and also a basic stretch for the bicep using a doorway or wall to hold onto.

Peptides have piqued my interest as well, but I'm not one to experiment with my health and after listening to the Huberman podcast, I'm in no rush to seek peptide use.

Here's another Huberman podcast on peptides.

Dr. Craig Koniver: Peptide & Hormone Therapies for Health, Performance & Longevity

In this Huberman Lab episode, learn about peptides' potential in improving health and performance. Learn effective dosages, safety tips, and expert insights.

www.hubermanlab.com

 

[rackcity24]

@awcopeland i have talked to a doctor and he had me do some external rotation workouts with bands. I haven't gone to a PT yet, I'm sure everything will have to prior authorized from my shitty insurance now. but that might be the route to go. Ive actually had good look going to a chiropractor and getting my shoulder adjusted. It worked for about a month, before it did it again. He said it would until my body gets used to it and would heal. Unfortunately he's not around my area anymore.

 

[awcopeland]

Here's another Huberman podcast on peptides.

Dr. Craig Koniver: Peptide & Hormone Therapies for Health, Performance & Longevity

In this Huberman Lab episode, learn about peptides' potential in improving health and performance. Learn effective dosages, safety tips, and expert insights.

www.hubermanlab.com

I’ll give it a listen maybe tomorrow. I honestly don’t see myself truly needing peptides (I’m still young and have never been really badly injured). But I do find human performance interesting.

 

[fatlander]

One month of daily BPC 157 from amino asylum healed a partially torn patellar tendon my dog had last year. The injury was nagging and would not heal for months. BPC plus an ozone round cleared it right up. BPC 157 is not approved for human use anymore because merc decided they want to pursue a designer patent, so they pushed the FDA to restrict it in the meantime. You can still buy it for research purposes. Your dog will thank you.


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[awcopeland]

One month of daily BPC 157 from amino asylum healed a partially torn patellar tendon my dog had last year. The injury was nagging and would not heal for months. BPC plus an ozone round cleared it right up. BPC 157 is not approved for human use anymore because merc decided they want to pursue a designer patent, so they pushed the FDA to restrict it in the meantime. You can still buy it for research purposes. Your dog will thank you.


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Ha, I never even thought of for my dog but he does have a nagging case of what the vet thinks is tendinitis. May I ask what size dog you have and dosage that you’ve used? Also, did you do this on your own investigation or did you have a more experienced mentor/doctor or some sort? Genuinely curious not trying to open a can of worms.

 

[SloppyJ]

Actually spoke to my doctor about this earlier this week. His thoughts were the same as mine that it's a great combo for recovery and healing.

I have a buddy that broke his thumb in a harescramble (yes i beat him, broken thumb was a poor excuse), had surgery, and immediately jumped on this. He swears by it as well.

My doctor was hopeful that RFK would change some things and allow compounding pharmacies to start producing it.

If you need a place for it, shoot me a message.

 

[SloppyJ]

One month of daily BPC 157 from amino asylum healed a partially torn patellar tendon my dog had last year. The injury was nagging and would not heal for months. BPC plus an ozone round cleared it right up. BPC 157 is not approved for human use anymore because merc decided they want to pursue a designer patent, so they pushed the FDA to restrict it in the meantime. You can still buy it for research purposes. Your dog will thank you.


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I love this. Glad I'm not the only one with pets around the house that have benefitted. Had good luck with AA too.

 

[Brock A]

I started BPC-157 injections on 1/7 for a torn rotator cuff. I had surgery on 1/16. I have nothing to compare it to as I had never used it before. But had a trusted friend with first hand experience coach me on it. He had great results with a broken elbow and a knee surgery. I have my post op appointment next week so we will see what my doc says about my recovery. I stopped the hard pain meds after day 2 and I am just taking Tylenol now with virtually no pain.

In the days leading up to my surgery, I made a comment to my wife that my shoulder literally feels fine and I don’t need the surgery anymore . She didn’t go for it. Doctor said that the tear was in better shape than they anticipated once she got in there.

I also used the limitless product. My wife injects me with an insulin needle and you can’t even feel it.

 

[K_pem]

I can confirm that BPC157 definitely aids in healing. I’ve used it on numerous occasions for knee injuries/post surgery as well as a partially torn pec; I know multiple others from the powerlifting community that have had good luck as well. It’s definitely something that athletes are using to shorten recovery times.

My typical dosage iirc was 200-250mcg x2 daily administered sub q. I do know of a legit source but idk how that source would feel about being publicly posted so I’ll refrain and you can PM for more info if needed.

I’m 2 weeks post op from a total left knee and I will be adding BPC back in here in the next couple weeks as I get more into the restrengthening phase

 

[fatlander]

Ha, I never even thought of for my dog but he does have a nagging case of what the vet thinks is tendinitis. May I ask what size dog you have and dosage that you’ve used? Also, did you do this on your own investigation or did you have a more experienced mentor/doctor or some sort? Genuinely curious not trying to open a can of worms.

I consulted my veterinarian before starting the treatment. He prescribed the dosage. My dog is a really big fella, 185 pounds. 250 mcgrams, twice a day.


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[rvalleyp]

If you have tumors, it can promote blood flow to tumors which can make them grow

There are nasal sprays available as well. Pills are available but it will take much longer to see the results. As far as I have read, for speedy effectiveness it goes. Needle (fastest), Nasal Spray, Pills (slowest). I totally understand about not wanting to hit yourself with a needle. I am currently using the nasal spray.

Have things gotten better yet? for myself, week three is where i really started to feel better. Im not 100% yet.

I have been using nasal spray BPC157 and TB500 for three weeks to heal a ruptured achilles tendon. I have seen improvement, i am pain free now, but my achilles tendon is not 100%, the rupture is visible still as the collagen fibers are not aligned yet, but it is changing, just slowly. After months of combating the rupture with PT, this has been the most promising thing so far. zero paint now, and I am simply doing the peptide with massage to help align collagen fibers.

I plan to step it up to the needle soon to see if i cant get it to 100% i hate needles, but i hate not being able to run more.

What dosage are you using with the nasal?

 

[The Fat Coyote]

10mg on the nasal spray. Whatever the solution that its in has dried out my sinuses pretty bad though. Its been a month now using the nasal spray 4x a day. pain is pretty much gone, i think i can run a mile if i had to, but my achilles rupture is still very visible.

Now I am injecting BPC157 + TB500 locally near the tendon, subcutaneously. Just started last night. Will keep you all posted here.

Peptides are already ushering in a new wave of snake oil salesman as is often seen in the nutraceutical and supplement world. There is very limited research on BPC-157 and there is NO GOOD RESEARCH (randomized controlled research) in humans demonstrating any clear benefit.

"However, to date, the majority of studies have been performed on small rodent models and the efficacy of BPC 157 is yet to be confirmed in humans."

Given how many people are now using this I am sure with time we will get some better data on its efficacy. Be very suspicious of the marketing materials and anecdotal evidence provided by the companies selling these supplements as they are almost always cherry picked and biased.

This podcast has a lot of good information on some of the current more common peptides in use. There is about 20 minutes dedicated specifically to BPC-157.

TB-500 is in the same boat more or less. Time will tell and these compounds may prove to have a benefit but as of yet we have no good evidence.

Huberman has been saying that there is alot of anecdotal evidence of people healing themselves with BPC 157, including olympians. I am leaning towards snake oil at this point, at least for my injury, because my injury is still visibly there. Pain however is nearly gone so its doing something. I just hope this experimenting doesnt come at the cost of harm. Huberman himself has said its very safe. Either way, ill let you all know what i find.

 

[Jbird1]

10mg on the nasal spray. Whatever the solution that its in has dried out my sinuses pretty bad though. Its been a month now using the nasal spray 4x a day. pain is pretty much gone, i think i can run a mile if i had to, but my achilles rupture is still very visible.

Now I am injecting BPC157 + TB500 locally near the tendon, subcutaneously. Just started last night. Will keep you all posted here.

Huberman has been saying that there is alot of anecdotal evidence of people healing themselves with BPC 157, including olympians. I am leaning towards snake oil at this point, at least for my injury, because my injury is still visibly there. Pain however is nearly gone so its doing something. I just hope this experimenting doesnt come at the cost of harm. Huberman himself has said its very safe. Either way, ill let you all know what i find.

What dosages are you injecting of the BPC157/TB500 combo? The blends are confusing to me (specifically, does 500mcg of “blend” equate to 250mcg of each peptide?

 

[awcopeland]

I’m curious how you guys are interpreting Huberman saying BPC157 is safe as it’s been placed on the do not compound list by the FDA? His last pod specifically on peptides basically messaged that because it’s on that list that he recommended staying away from the “grey/dark grey” market. I’m not arguing it’s efficacy but the way I interpreted it was that PDA was still allowed to be compounded and has the same result. Just curious if I’m absorbing old info.

 

[mtbraun]

I’m curious how you guys are interpreting Huberman saying BPC157 is safe as it’s been placed on the do not compound list by the FDA? His last pod specifically on peptides basically messaged that because it’s on that list that he recommended staying away from the “grey/dark grey” market. I’m not arguing it’s efficacy but the way I interpreted it was that PDA was still allowed to be compounded and has the same result. Just curious if I’m absorbing old info.

The reasons for some peptides being blacklisted (like BPC-157) and others allowed is very unclear. Likely influenced by big pharma's attempts to create IP and/or some toxic stew they can shill to the uninformed.

To be clear, Huberman was speaking to the source of the peptide, not the efficacy. He's right in urging caution around "research" based suppliers. Also see Peter Attia and Craig Koniver for a good perspective on peptides from an actual clinician.

I'm hopeful under the new administration BPC and other useful peptides will be allowed to be compounded.

PDA and BPC-157 are both comprised of 15 amino acids, but their structure is different. PDA and CJC-1295 are two good alternatives to BPC-157.