That’s a rabbit hole question with 100’s of variants with in multiple sizes, spines, fletching, wraps FOC and 20 other things that can come up. It’s all personal preference and set-up with intended game and hunting area not to mention max distance you're wanting to shoot. I go deep into the muck but here’s what I know I like for my style and set up. I bowhunt elk in Idaho in some timber patches and old burns with big meadows in between. I shoot 70-75 lb bows with a 30.5 inch draw length I carry expandable heads for longer shots and fixed for thicker brush close quarter shots. I take a .165 300 spine arrows cut them as close as I can safely get to the launcher blade. I use mostly aae max hunters and I go back in forth with wraps or lighted nocks this year wraps, the lighted nocks with small diameter just don’t hold up for a ton of work especially for me when I get over 500 grains. I’m running VAP v1’s again this year not tko and 200-220 grains up front TAW is like 520-540. I get plenty of speed with my original specs and it makes for a hard hitting reasonable to tune arrow with a good fixed head. I’ve gone down as low as 440 and is high as 650 on arrow weight and killed elk. I like low-mid 500 grain arrows it’s a good compromise. I also prefer the .165.166 4mm arrow for windy days I don’t think it aids penetration enough to matter but in 7 plus mile an hour wind past 50 yards it’s a slight advantage over 6.5 and very slight over 5mm but I’ll take any advantage I can muster. I’m also still playing with glue in broadheads I like the lack of outsert and the long glue in portion makes a strong connection and I still believe it makes it easier to shoot what might be a slightly weak arrow. Like I said rabbit hole and none of it probably matters but I love to tinker in the off season, hunting is my only hobby.