I took this shot on a whitetail that I had previously made a poor shot on and didn't want to push any further. 30 yards, deer not looking at me. I hit about 4 " below the jaw line, dead center of the neck. It did not work as planned, and the deer bolted.
I waited an hour, tracked and shot the deer in it's bed almost a 1/2 mile away. This time in the lungs. The autopsy revealed the arrow had passed through between the jugular veins and spine, hitting nothing important at all.
In that circumstance, I'd do it again. On an un-wounded deer, no.
Jeremy