I've shot them in my PRC and Creed for the last few years. Creed was a first this year. They're not a bonded or mono bullet. They're super soft and explosive. Which for deer and antelope isn't a bad thing. They go in and cause a ton of damage. From 90-725 it seems to do really well.
I shoot the Hornady factory 143gr 6.5 creedmoor rounds out of a Fieldcraft. Work great, no complaints.
If I'm blacktail hunting in areas where I know any shot will be under 300 yards (usually WAY under) I carry the Barnes 127 LRX's instead because they don't make as much of a mess.
6mm Creedmoor,103 gr. eld-x . Took 6 hogs and red sheep and axis. The bullet works to good for me. Lots of meat lose from the hydrostatic shock on the sheep and axis. Both lung shots blew up ribs and part of front shoulder (bloodshot). Pigs were head shot no worries there. Will get pic's next trip. Switching to eld-m.
Entrance side of my mule deer. Shooting a 6.5 PRC with factory 143 eld-x. 256 yds.
My wife’s deer look about the same with at 187 yards. Both deer were lung shot, mine clipped the heart. Exits on both. Neither deer went more than 5 feet and died.