After taking a WFR class my first aid kit shifted to more of an active piece of equipment instead of some haphazardly put together kit of duct tape and a leatherman stuffed into the bottom of a backpack never to be opened until shit hits the fan. It's geared for first response to a patient whether that's myself on a solo trip, a friend or complete stranger- a broken leg is a broken leg regardless of activity. Having to constantly break into a vacuum sealed bag would ultimately defeat what I am trying to accomplish- a lightweight bag that has pockets to keep things organized inside the kit without stuff rolling around or falling out. If I am trying to stop the bleeding on a deep laceration, i don't want to be sifting through pills and CPR masks to get to more 4x4s. You might be thinking my kit is heavy but at a meager 10 oz it is still capable to treat fractures, cuts, allergic reactions and even cardiac arrest until a safe evac or successful rescue. Thanks for the suggestion though, I've do have a cryovac I could work with