They will pair. I have a 5500 Fire Weather, and it pairs with apps. 4DOF pairs easily, Applied Ballistics has given me some trouble pulling data over, but it is an issue with AB.
That said, use density altitude and all you need is one number.
My conclusion, from reading on here, not experience yet, is that wind calling involves figuring out more than just wind at the shooter. You could get the weather vane set up and have any of the 5500 calculate wind direction and speed, but it is probably more trouble than it is worth.