Sure, I live on the east coast and generally shoot and hunt here around 2000’ DA. When I travel west to hunt I have done so between 5000’ and 11000’ elevation.
When I check zero after flying west, my 100-yard zero generally does not shift—if it does, its from the baggage handlers, not the change in elevation.
You’ll see an increase in how far off your low-elevation dope is as you go up in DA and as you increase range. Looking at 2 rifles, a 270 and a 6.5cm and comparing 2000’ to 9000’ DA, at 300 yards my dope is off either less than .1mils or .1 mils, and both rifles are off .2 mils at 500 yards (So low elev solution is 3.1mils, 9000’ solution is 2.9, difference is .2mils). That equates to about .35moa or less at 300 (about 1.1” impact distance) and about .75moa at 500 (about 3.75” impact distance).
Keep in mind that amount of error is in addition to the precision of my equipment and my wobble, so it’ll very easily cause a miss/bad hit on a deer-sized target at 500 yards that would otherwise have been a good hit. At longer range it’ll be worse.